Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2504)
Related Products (2504)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Antileishmanial agent-30
0 ImagesCat. No.: HY-162833Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC50, CC50, and SI of 0.2 μM, >100 μM and >500 for L. donovani.
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Z-Antiepilepsirine
0 ImagesCat. No.: HY-N11031CAS No.: 111479-04-0Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum.
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Betulonaldehyde
0 ImagesBetulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice.
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Fenazaquin-d13
0 ImagesCat. No.: HY-W739267Synonyms: XDE-436-d13; EL-436-d13Fenazaquin-d13 (XDE-436-d13) is the deuterium labeled Fenazaquin (HY-117397). Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide.
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Oltipraz (GMP)
0 ImagesCat. No.: HY-12519GCAS No.: 64224-21-1Synonyms: RP 35972 (GMP); NSC 347901 (GMP)
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Myricitrin (Standard)
0 ImagesMyricitrin (Standard) is the analytical standard of Myricitrin. This product is intended for research and analytical applications. Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects.
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KAI-407
0 ImagesCat. No.: HY-18746CAS No.: 1513879-18-9KAI-407 is an orally active inhibitor of Plasmodium PI4K kinase, which can broadly inhibit multiple stages of the parasite lifecycle. KAI-407 exhibits EC50s of for the blood stage of malignant Plasmodium of 81 nM; for the liver schizonts of P. yoelii of 88 nM; and IC50s for the liver schizonts and dormant bodies of P. cynomolgi of 0.64 μM and 0.69 μM respectively. KAI-407 can prevent Plasmodium berghei infection 100%. KAI-407 can be used for the study of vivax malaria.
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Hexamidine-d12
0 ImagesCat. No.: HY-W740485CAS No.: 1286461-12-8Hexamidine-d12 is the deuterium labeled Hexamidine. Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
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MMV665916
0 ImagesCat. No.: HY-W026467CAS No.: 896356-25-5MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
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Amphotericin B trihydrate
0 ImagesCat. No.: HY-B0221ACAS No.: 1202017-46-6Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.
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Antitrypanosomal agent 15
0 ImagesCat. No.: HY-155103CAS No.: 2961381-94-0Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study.
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Ethopabate-d5
0 ImagesCat. No.: HY-W702966CAS No.: 2469244-16-2Synonyms: Ethyl pabate-d5Ethopabate-d5 (Ethyl pabate-d5) is the deuterium labeled Ethopabate (HY-B2138). Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
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(R)-Hydroxychloroquine phosphate
0 ImagesCat. No.: HY-B1370ECAS No.: 2488706-20-1Synonyms: (R)-HCQ phosphate(R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats.
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α-Artemether
0 ImagesCat. No.: HY-137217CAS No.: 71939-51-0Synonyms: Methoxyα-Artemether is an antimalarial compound.
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8-Acetonyldihydrochelerythrine
0 ImagesCat. No.: HY-N18179CAS No.: 15575-49-28-Acetonylidihydrochelerythrine is a benzophenanthridine alkaloid found in the stem bark of Zanthoxylum gilletii. 8-Acetonylidihydrochelerythrine inhibits growth of Chloroquine (HY-17589A)-resistant and Chloroquine-sensitive Plasmodium falciparum strains. 8-Acetonylidihydrochelerythrine can be used for the research of malaria.
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Parthenin
0 ImagesParthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections.
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Anticancer agent 75
0 ImagesCat. No.: HY-147971CAS No.: 2414491-13-5Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial.
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Ronidazole-d3
0 ImagesCat. No.: HY-B0565SCAS No.: 1015855-87-4Ronidazole-d3 is the deuterium labeled Ronidazole (HY-B0565). Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery.
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Antimalarial agent 8
0 ImagesCat. No.: HY-145704CAS No.: 2715222-97-0Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria.
